Not all patients with CLL call for therapy. In spite of all current advancements, the iwCLL however endorses watchful observation for patients with asymptomatic ailment.86 This recommendation relies on at the least two randomized trials evaluating observation to either chlorambucil monotherapy or fludarabine, cyclophosphamide and rituximab (FCR).103,104 Both trials concluded https://allano520jrz7.wikirecognition.com/user