Schematic representation of activated and inhibited Wnt/β-catenin pathway. “WNT ON condition�? On ligation of Wnts for their receptors made up of frizzled proteins and LRP5/6, the cytoplasmic protein DVL is activated and induces the suppression of GSK3β. Subsequently, stabilized β-catenin translocates to the nucleus and binds to TCF/LEF transcription aspects https://virgilv752kpt5.activosblog.com/28228736/t-1101-tosylate-things-to-know-before-you-buy