In this article, we show that conolidine, a natural analgesic alkaloid Utilized in classic Chinese medicine, targets ACKR3, thus giving supplemental evidence of a correlation involving ACKR3 and discomfort modulation and opening alternative therapeutic avenues for the remedy of chronic discomfort. All logos, registered emblems and service-marks described on https://what-is-kratom10986.blogdosaga.com/31731634/the-5-second-trick-for-what-is-conolidine