, ritonavir) or discontinuation of the cytochrome P450 3A4 inducer like rifampin, carbamazepine, and phenytoin, could cause an increase in codeine plasma concentrations with subsequently better metabolism by cytochrome P450 2D6, resulting in greater morphine degrees, which could maximize or extend adverse reactions and could induce possibly fatal respiratory depression. https://caideninpmj.blogstival.com/54339559/considerations-to-know-about-akorn-codeine