In this article, we exhibit that conolidine, a natural analgesic alkaloid used in conventional Chinese medicine, targets ACKR3, therefore furnishing additional evidence of a correlation between ACKR3 and agony modulation and opening substitute therapeutic avenues for the cure of chronic agony. All trademarks, registered trademarks and service-marks described on https://jonathanj580utt2.techionblog.com/profile