Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors in the central anxious system, conolidine modulates alternate molecular targets. A Science Advances analyze uncovered that conolidine interacts While using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://franciscolhhgn.aioblogs.com/90518454/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview